Molecular Docking and Molecular Dynamics Simulation studies of DHFR inhibitors in Plasmodium falciparum
نویسندگان
چکیده
منابع مشابه
Molecular docking studies on DMDP derivatives as human DHFR inhibitors
Molecular docking is routinely used for understanding drug-receptor interaction in modern drug design. Here, we describe the docking of 2, 4-diamino-5-methyl-5-deazapteridine (DMDP) derivatives as inhibitors to human dihydrofolate reductase (DHFR). We docked 78 DMDP derivates collected from literature to DHFR and studied their specific interactions with DHFR. A new shape-based method, LigandFit...
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ژورنال
عنوان ژورنال: Canadian Journal of Biotechnology
سال: 2017
ISSN: 2560-8304
DOI: 10.24870/cjb.2017-a11